Atezolizumab, vemurafenib, and cobimetinib (TRICOTEL) in patients with melanoma with CNS metastases: a multicenter, open-label, single-arm, phase 2 study

Background Focused remedy and immunotherapy have proven intracranial exercise in melanoma with CNS metastases, however there’s an unmet want, particularly for sufferers with symptomatic CNS metastases. We aimed to guage atezolizumab together with cobimetinib or vemurafenib plus cobimetinib in sufferers with melanoma with CNS metastases. strategies TRICOTEL was a multicenter, open-label, single-arm, section 2 examine … Read more